https://rorreceptor.com/index.....php/acculturative-st
We herein report that deletion of mTOR in dental epithelia caused flawed development of multiple cell levels associated with the enamel organ, which culminated in enamel malformation and cystogenesis. Especially, cells for the stellate reticulum and stratum intermedium were defectively formed, causing cystic modifications. The pre-ameloblasts didn't elongate along the apical-basal axis and persisted vigorous expression of Sox2 and P63, which are generally downregulated d
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