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The impact of substituent kind and position ended up being examined. The partnership between framework and task was also preliminary analyzed.The our past study synthesized the chrysin-chromene-spirooxindole hybrids 3, and additional discovered compound 3e had good antitumor activity against A549 cells in vitro through multi-target co-regulation for the p53 signalling path to inhibit the proliferation of A549 cells. This research ended up being designed to evaluate the anti

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