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How Does ADHD Medication Work? ADHD is treated by taking stimulants. They regulate the levels of neurotransmitters (two brain chemicals) which transmit messages between neurons to improve attention and reduce excessive hyperactivity. 20 % of people are not sensitive to stimulants such as methylphenidate or amphetamine. This could be due to their body chemistry or other medications they are taking. What are the symptoms of ADHD? If you suspect your child has ADHD and you suspect it, first visit their doctor. They will do