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Level of Evidence 3. Systematic review and meta-analysis of randomized controlled trial (RCT). The aim of this study was to evaluate radiological and clinical outcomes of acute traumatic thoracolumbar fractures in skeletally mature patients treated with orthosis, versus no immobilization. Orthosis is traditionally used in conservative treatment of thoracolumbar fractures. However, recent studies suggest no benefit, and a possible negative impact in recovery. Databases were searched from inception to June 2019. Studies were selected in

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