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The Most Effective ADHD Medication For Adults Most of the medications used to treat ADHD fall into two categories: nonstimulants and stimulants. stimulants like methylphenidate and amphetamines increase activity in brain areas that regulate attention and behavior. Nonstimulants such as guanfacine, Clonidine, atomoxetine, and others, are slower than stimulants, but they aid in improving concentration and attention as well as impulsivity. They also appear to decrease anxiety which is
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