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Here, we review the components that the UPS hires to regulate mitochondrial purpose and effectiveness. For this function, we illustrate exactly how Ubiquitin together with Proteasome be involved in diverse high quality control paths that protect entry into the mitochondrial compartment. A focus will be achieved regarding the UPS-mediated control over the fungus mitofusin Fzo1 which gives ideas to the complex regulation of this specific necessary protein in mitochondrial fusion. We finally diss

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