https://www.selleckchem.com/pr....oducts/seclidemstat.
Background In knee osteoarthritis (OA), there is more pronounced cartilage damage in the medial compartment ('lesion zone' than the lateral compartment ('remote zone'. This study fills a gap in the literature by conducting a systematic comparison of cartilage and chondrocyte characteristics from these two zones. It also investigates whether chondrocytes from the different zones respond distinctly to changes in the physical and mechanical microenvironment using 3D porous scaffolds by changing stiffness and pore size. Methods Carti
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