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The Most Effective ADHD Medication For Adults The majority of ADHD medications fall into two categories: stimulants or non-stimulants. The stimulants like methylphenidate (Provigil) and amphetamines function by increasing activity in parts of the brain that regulate the behavior and attention. Non-stimulants, such as guanfacine the atomoxetine and clonidine are slower than stimulants, but they aid in improving focus and attention, as well as impulsivit
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