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Does ADHD Medication Work? If someone is given ADHD medication, they are concerned about how long the medication will last and if it works. Here are some simple solutions. Stimulants adjust brain chemicals that transmit messages regarding attention and activity. Dopamine, norepinephrine and other brain chemicals are included. They are the first line of treatment for adults suffering from ADHD. 1. Stimulants Stimulants are among the most commonly used medications to manage ADHD. They alter the activity of neurotransmitters in the brain (like dopamine), which helps

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