https://www.selleckchem.com/products/lly-283.html
Upregulation of miR-181a-5p (via transfection) inhibited inflammation of, and HMGB1 expression by, LPS-induced PC12cells. HMGB1 overexpression reversed the anti-inflammatory effects of miR-181a-5p. Dual-luciferase assays confirmed that HMGB1 was a direct target of miR-181a-5p. miR-181a-5p attenuated the inflammatory response of LPS-induced PC12cells by directly inhibiting HMGB1; thus, miR-181a-5p may serve as a therapeutic target in SCI. miR-181a-5p attenuated the inflammatory response of LPS-induced PC12 cells by directly inhibiting HM
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