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The patients when you look at the control group will take mecobalamin (MeCbl) pills orally, one tablet each, three times every single day for 30 days. The primary outcome measures is the evaluation scale of peripheral neurotoxicity of chemotherapeutic medications according to the European business for analysis and Treatment of Cancer Quality of Life Questionnaire-CIPN 20-item (EORTC QLQ-CIPN2 together with peripheral neurotoxicity evaluation ratin
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