https://www.selleckchem.com/
Background Acne vulgaris is a common dermatologic disease that causes significant social and psychological morbidity. Isotretinoin, as a vitamin A derivative, is the most effective agent in the treatment of acne. Evidence suggests that isotretinoin's therapeutic function is independent of hormonal mediation; however, the effect of isotretinoin on serum androgens and precursor androgen levels in humans remains unclear. Objective Herein, we aim to investigate the effect of low-dose isotretinoin on androgen levels in women and postulate the role of concomitant
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