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The purpose of this study was to evaluate solitary nucleotide polymorphisms (SNPs) in FOS, CASP8 and MMP2 and also to figure out their SNP-SNP interactions with CRISPLD2 variants into the chance of nonsyndromic cleft lip with or without cleft palate (NSCL±P) within the Brazilian population. The SNPs rs1046117 (FOS), rs3769825 (CASP8) and rs243836 (MMP2) were genotyped using TaqMan allelic discrimination assays in a case-control sample co
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