https://www.selleckchem.com/
05). Differentiation of healthy donor monocytes in SSc patient-derived plasma conferred the immunophenotype of SSc patient macrophages (n=13, p less then 0.05). Transwell experiments demonstrated that co-culture of SSc macrophages with SSc fibroblasts induced fibroblast activation (n=3, p less then 0.05). CONCLUSION These data demonstrate the activation profile of SSc macrophages is pro-fibrotic. SSc macrophages are activated under basal conditions, and release mediators and express surface markers associated with both alternative and inflammatory macrophag
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