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The PHLPP1 model was then used in docking interaction analysis and Molecular Dynamics Simulation, to study binding pockets and interactions of PHLPP1 ligands and finding actively contributing residues in binding pocket. In final step, Free Energy Estimation was performed to observe ligand binding's quantitative characteristics.Uterine fibroids (UF) or leiomyomas can be presented in post-menopausal women. The present study was aimed to examine the inhibitory and protective (anti-proliferative and apoptotic) effect of the obovatol (O in
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