https://www.selleckchem.com/pr....oducts/GDC-0980-RG74
While the alteration of I receptors has been associated with neurodegenerative and psychiatric disorders, among other brain dysfunctions, I selective agonists are also capable of inducing analgesia in models of chronic pain, improving cognition and inducing hypothermia and neuroprotection. However, the literature evaluating the antidepressant-like potential of I ligands is scarce and showed mixed results, whereas some studies reported antidepressant-like effects for certain I ligands others denied them. In this context, we evalu
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