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4) among carvedilol users (comparator arm) compared to corresponding to an adjusted hazard ratio (aHR) of 0.97 (95% confidence interval [CI] 0.94, 1.01). Similarly, metoprolol was not associated with a significant increase in the risk of secondary outcomes including insulin initiation aHR of 0.98 (95% CI 0.93, 1.04) and severe hyperglycemic events aHR of 0.98 (95% CI 0.93, 1.02). In this large study of older adults with HF and diabetes, initiation of metoprolol compared to carvedilol was not associated with an increase in the risk of cl
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