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Stroke is a type of cerebrovascular illness. Inflammation-induced neuronal demise is one of the crucial factors in stroke pathology. Propofol has been shown to ameliorate neuroinflammatory damage, nevertheless the exact process of their neuroprotective role continues to be becoming totally elucidated. In our study, we unearthed that irritation was triggered in ischemic cortical neurons, in addition to appearance of nucleotide-binding domain, leucine-rich-

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