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Based on these data, our diabetic vascular chip provides a promising tool for studying vascular endothelial function, and SELENOS may be a novel target for prevention and treatment of diabetic macrovascular complications. OBJECTIVES To investigate the effect of hepatitis C virus (HCV) infection treatment with direct-acting antiviral (DAA) drugs on patients' mood, sleep quality, and quality of life (QoL). METHOD Chronic HCV infected patients receiving DAAs were evaluated prospectively. Patients were evaluated before the beginning of treatm