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Wuhan, the epicenter of the coronavirus diseases 2019 outbreak, was locked down on January 23, 2020. We aimed to investigate the barriers to the physical prevention, negative attitudes, and anxiety levels. A online cross-sectional survey was conducted with the people living in Wuhan between March 12th and 23rd,2020. Of a total of 2411 complete responses, the mean and standard deviation for the total physical prevention barriers score was 19.73 (standard deviation±5.3; range 12-45) out of a possible score of 48. Using a cut-off score of

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