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48% (n=620,986), acute CVA 0.13% (n=22,522), and all-cause mortality 0.31% (n=55,632). When compared to other groups, patients with a higher CVRS were readmitted more frequently for AF/AFL [odds ratio (OR) 2.43; 95% confidence interval (CI) 2.41-2.45, P.0001), acute CVA (OR 3.96; 95%CI 3.85-4.08, P.0001), and all-cause mortality (OR 2.19; 95%CI 2.14-2.24, P.0001). In this large contemporary cohort, a CHADS2VA2SC score≥6 identified patients without known prior atrial arrhythmias at an elevated risk of developing AF/AFL or acu

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