https://mirnamimic.com/index.p....hp/mind-body-physica
Airway parts from asthmatics with increased mucus load revealed higher LASI expression in MUC5AC+ goblet cells after multi-fluorescent in-situ hybridization and immunostaining. LPS- or IL-13-induced LASI transcripts were mainly enriched in the nuclear/perinuclear area and were associated with increased ICAM-1, IL-6, and CXCL-8 expression. Blocking LASI expression decreased the LPS or IL-13-induced epithelial inflammatory factors and MUC5AC phrase, recommending that the n
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