https://tyrphostinag-1478.com/....surface-changes-of-c
We show that regulating T (Treg) cells gather in venous blood clots and regulate thrombolysis by managing the recruitment, differentiation and matrix metalloproteinase (MMP) activity of monocytes. We describe a clot Treg populace that forms the matricellular acid- and cysteine-rich necessary protein (SPARC), show that SPARC enhances monocyte MMP activity and therefore SPARC+ Treg are very important for blood coagulum resorption. By evaluating different treatment times, we define a therapeutic window of Treg expans
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