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https://www.selleckchem.com/pr....oducts/bip-inducer-x
Plausible parameter maps were obtained with RGD from single-shell in vivo data. The plausibility of these maps was shown to be determined by the initialization. Tests with simulated lesions inserted into the in vivo data revealed that the RGD approach cannot distinguish free water from tissue mean-diffusivity alterations, contrarily to the nonlinear least-squares algorithm. The RGD FWE-DTI method has limited specificity; thus, its results from single-shell data should be carefully interpreted. When possible, multishell acquisi

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