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ess then 0.05) were all significantly higher after CP. On long-term follow-up, DP patients were more likely to have postoperative exocrine (RR 0.56; 95% CI 0.37 to 0.84; P less then 0.05) and endocrine (RR 0.27; 95% CI 0.18 to 0.40; P less then 0.001) insufficiency. There was no statistically significant difference in transfusion requirement, postoperative mortality, reoperation, and tumor recurrence. Conclusion CP is associated with significantly higher morbidity and clinically relevant pancreatic fistula. CP should only be reserved f