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Background Alcohol and cannabis use are highly comorbid. Objective We evaluate if alcohol use and/or alcohol use disorder symptoms predict experiences of cannabis use disorder symptoms among adolescents and young adults and whether the relationships differ based on frequency of cannabis use, recency of cannabis initiation and age. Method Data were drawn from five annual surveys of the National Survey on Drug Use and Health (2014-2018) to include adolescents and young adults (age 12 to 21 years) who reported using cannabis and alcohol a

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