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8%), compared to 4.2% in nonvariant (all p less then 0.001). Metastatic disease in mucinous (3.3%) was similar to nonvariant (p=0.2). Estimated 10-year overall survival was highest in mucinous (78.0%), followed by nonvariant (71.1%), signet ring cell (56.8%), ductal (56.3%), adenosquamous (20.5%), sarcomatoid (14.6%) and neuroendocrine (9.1%). At multivariable analysis, mortality was higher in ductal (HR 1.38; p less then 0.001), signet ring cell (HR 1.53; p less then 0.01), neuroendocrine (HR 5.72; p less then 0.001), sarcomatoid (HR 5

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