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ACCESSIBILITY AND IMPLEMENTATION Genotyping methods which use these priors tend to be implemented when you look at the updog R bundle available on the Comprehensive R Archive Network https//cran.r-project.org/package=updog. All rule needed to reproduce the outcomes of this article can be obtained on GitHub https//github.com/dcgerard/reproduce_prior_sims. SUPPLEMENTARY IDEAS Supplementary data are available at Bioinformatics on the web. © The Author(s) 2019. Published by Oxford University Pr