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The cells survival rate, vitality and the apoptosis were detected by MTT, lactate dehydrogenase (LDH) and TUNEL staining assay Kit, respectively. Results Our present study showed that baicalin significantly improved LV hemodynamic parameters and myocardial apoptosis in myocardial I/R injury rats. Furthermore, we found that baicalin could down-regulation the protein expression of CaSR, but up-regulation the protein expression of ERK1/2. Furthermore, when the cells were pretreatment with ERK1/2 inhibitor PD98059, the cells survival rate
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