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Sequence analysis of the gene in , revealed no macrolide resistance of to Clarithromycin. Thus, the use of these antibiotics should be restricted to prevent the development of macrolide-resistant in Iran. Sequence analysis of the 23S rRNA gene in M. pneumoniae , revealed no macrolide resistance of M. pneumoniae to Clarithromycin. Thus, the use of these antibiotics should be restricted to prevent the development of macrolide-resistant M. pneumoniae in Iran. Introduction Oxytocin (OT) has been proposed to assist in the regulation of bone re

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