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All rights reserved. For permissions, e-mail [email protected] operating vancomycin surgical prophylaxis are poorly comprehended. In a national VA cohort with manually validated information, surgical specialty (cardiac, orthopedics) and perception of high facility MRSA prevalence-not MRSA colonization-- had been the primary drivers of prescribing. Beta-lactam sensitivity ended up being the second-most typical reason. These data may inform peri-operative stewardship

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