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It is well known that mixed collectors can effectively strengthen the flotation of low-rank coal. However, less concern has been paid to the detachment of low-rank coal flotation using mixed collectors. In this study, the force of air bubble detachment from low-rank coal surface treated by oleic acid (OA), dodecane (D), and oleic acid-dodecane (OA-D) collector mixture was investigated using microforce balance. The results showed that the process of bubble detachment from the low-rank coal surface was divided into three stages relaxation