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nce occur, depending on covariate availability, and provide guidance in variable selection for optimal WNV human illness modeling. These results suggest human WNV illness in the Chicago area may be associated with fewer, but increasingly critical, key variables at finer scales. Given limited resources, these findings suggest large variations in model performance occur, depending on covariate availability, and provide guidance in variable selection for optimal WNV human illness modeling.By focusing on high experimental control and realist

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