https://www.selleckchem.com/pr....oducts/Tranilast.htm
The zinc finger transcription factor Mxr1p regulates the transcription of genes involved in methanol, acetate and amino acid metabolism of the industrial yeast Pichia pastoris (a.k.a. Komagataella phaffii) by binding to Mxr1p response elements (MXREs) in their promoters. Here, we demonstrate that Mxr1p is a key regulator of ethanol metabolism as well. Using transcriptomic analysis, we identified target genes of Mxr1p that mediate ethanol metabolism, including ALD6-1 encoding an aldehyde dehydrogenase. ALD6-1 is essential for ethanol m
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