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05). The reduction of VEGF and CoX-2 expression of pterygial vascular endothelial cells in group 1 were statistically significant compared to group 2 and group 3 (p less then 0.05). There were significant correlations between COX-2 and VEGF expression of pterygial tissues within the three groups (p less then 0.05). Conclusion The present findings suggested that the topical pranoprofen 0.1% could reduce the expression of VEGF and COX-2 in primary pterygium. We confirmed that treatment with pranoprofen offers advantages in early intervent
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