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WLBU2 and D8 (all 8 valines would be the D-enantiomer) efficiently destroy both gram-negative and -positive bacteria, but WLBU2 is toxic and D8 non-toxic to eukaryotic cells. We explore protein secondary framework, location of peptides in six lipid design membranes, alterations in membrane layer structure and pore evidence. We claim that protein additional structure is not a critical determinant of bactericidal activity, but that membrane thinning and dual area

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