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https://www.selleckchem.com/pr....oducts/imidazole-ket
s were decreased significantly (P0.05). IL-6, IL-1 beta, TNF-α levels were significantly decreased (P0.05). IL-10 level was significantly increased (P0.05). The ratios of cleaved caspase-3/caspase-3, cleaved caspase-9/caspase-9, and Bax/Bcl-2 were significantly reduced (P0.05), showing that the pathological damage degree and the apoptosis rate was significantly lower. HIF-1α overexpression has protective effects on renal ischemia-reperfusion rats by improving pathological injury and immune function, redu

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