https://www.selleckchem.com/pr....oducts/pf-06873600.h
A significant reduction of encrusted calcifications was observed in 88% of cases. Renal function improved in 71% of the patients. Nevertheless, poor tolerance of the treatment and side effects were common, affecting 71% of patients, with Gram-negative bacilli urinary tract infections (53%) being the most frequent. At last follow-up, 4 patients (23.5%) progressed to end-stage renal disease and only 1 had a clinical relapse. Encrusted urinary tract infections are rare, characterized by a severe renal and overall prognosis in the absen
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