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. At 8 years the prevalence of MR ≥3+ was significantly higher in the study group (15.6% vs 2.1%, P less then 0.001) as was the use of diuretics, beta-blockers and angiotensin-converting enzyme inhibitors/angiotensin-receptor blockers. Interestingly, even in the control group, a gradual progression of MR was observed because 13.3% of the patients had MR ≥2+ at 8 years with a significant increase over time (P less then 0.001). CONCLUSIONS Residual MR more than mild at hospital discharge is associated with lower durability of mitral
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