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OBJECTIVES To compare the results regarding the flavonoid chrysin because of the ramifications of the neurosteroids progesterone and allopregnanolone on depression-like behavior in ovariectomized rats and evaluate the participation of γ-aminobutyric acid-A (GABAA) receptors during these actions. METHODS Ovariectomized female Wistar rats were subjected to the locomotor task test and forced swim test. The animals had been assigned to eight treatment groups automobile, chrysin (1 mg/kg), progester