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atient, but careful attention is needed to integrate these services with the current health care delivery system in place and ensure quality care to the patients. Stereotactic body radiotherapy (SBRT) for tumours ≥5 cm is poorly studied and its utility and feasibility is uncertain. We here report the Karolinska experience of SBRT in this setting. All patients had a gross tumour volume (GTV) ≥70 cc, a prescribed physical dose of at least 40 Gy and received treatment between 1995-2012. We included 164 patients with 175 tumours located in
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