https://www.selleckchem.com/products/ABT-263.html
Canine hypoadrenocorticism is an immune-mediated endocrinopathy that shares both clinical and pathophysiological similarities with Addison's disease in humans. Several dog breeds are overrepresented in the disease population, suggesting that a genetic component is involved, although this is likely to be polygenic. Previous research has implicated as a potential susceptibility gene. CTLA4 is an important regulator of T cell function and polymorphisms/mutations in have been associated with a number of autoimmune phenotypes in both humans
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