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81, 95% CI 1.38-2.36; p 0.001 and HR 1.35, 95% CI 1.07-1.72, p= 0.012), while no significant difference was observed between intermediate and poor LIPI groups in terms of OS (HR 1.01, 95% CI 0.82-1.23, p= 0.82), but not for PFS (HR 1.27, 95% CI 1.00-1.61, p= 0.048). In addition, LIPI score was significantly associated with disease control rate and objective response rate (both p 0.0001). Prognosis of patients with pretreatment LIPI score of 2 is poorer than those with LIPI score of 0-1 among ES-SCLC who received first-line platin