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The extract significantly attenuated brain infarction and neuronal death in the cerebral cortex and hippocampus. Conclusion We demonstrated the neuroprotective effects of T. triandra leaf extract against cerebral IR injury in mice.Objective Extracts of Anchomanes difformis (AD) are used in folkloric medicine to treat several diseases and infections. However, their roles in mitochondrial permeability transition pore opening are not known. Materials and Methods The viability of mitochondria isolated from Wistar rat liver used in this exper

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