https://www.selleckchem.com/pr....oducts/gsk2126458.ht
Signifying the 2-compartments/1-disease paradigm, allergic rhinoconjunctivitis (ARC) and asthma (AA) are prevalent, comorbid conditions triggered by environmental factors (eg, house dust mites [HDMs]). However, despite the ubiquity of triggers, progression to severe ARC/AA is infrequent, suggesting either resilience or adaptation. We sought to determine whether ARC/AA severity relates to maladaptive responses to disease triggers. Adults with HDM-associated ARC were challenged repetitively with HDMs in an aeroallergen challenge chambe
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