https://www.selleckchem.com/pr....oducts/Novobiocin-so
Older adults have worse outcomes after sepsis than young adults. Additionally, alterations of the gut microbiota have been demonstrated to contribute to sepsis-related mortality. We sought to determine if there were alterations in the gut microbiota with a novel sepsis model in old adult mice, which enter a state of persistent inflammation, immunosuppression and catabolism (PICS), as compared to young adult mice, which recover with the sepsis model. Mixed sex old (∼20 mo) and young (∼4 mo) C57Bl/6J mice underwent ce
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