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Preoperative hemoglobin A1C levels were associated with development of mediastinitis, stroke, pneumonia, sepsis, renal failure and mortality after cardiac surgery. Key WordsHemoglobin A1C, Cardiac surgery, Complication, Meta-analysis. Preoperative hemoglobin A1C levels were associated with development of mediastinitis, stroke, pneumonia, sepsis, renal failure and mortality after cardiac surgery. Key Words Hemoglobin A1C, Cardiac surgery, Complication, Meta-analysis. To comparatively investigate the efficacy, safety and complications of