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This review aims at updating on the most recently discovered mechanisms of tumorigenesis and the pivotal role of GxE interactions. 2020 Translational Lung Cancer Research. All rights reserved.Research has established a strong association between asbestos exposure and malignant mesothelioma, a deadly form of cancer. Since the early 1980's many countries have restricted or banned the production of asbestos, leading to a decline of occupational asbestos exposure in many industrialized countries. However, some countries continue to use asbes
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