https://www.selleckchem.com/pr....oducts/sodium-2-1h-i
The package is available for download for research purposes at https//projects.iq.harvard.edu/bayesmendel/panelpro.DNA loop extrusion by condensins and decatenation by DNA topoisomerase II (topo II) are thought to drive mitotic chromosome compaction and individualization. Here, we reveal that the linker histone H1.8 antagonizes condensins and topo II to shape mitotic chromosome organization. In vitro chromatin reconstitution experiments demonstrate that H1.8 inhibits binding of condensins and topo II to nucleosome
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