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HLA-A*30171 differs from HLA-A*30010101 by one nucleotide substitution at position 821 in exon 4. The aim of this study was to evaluate the levels of serum and gingival crevicular fluid (GCF)human beta-defensin-2 (hBD-2), an antimicrobial peptide that takes roles in inflammatory diseases, in patients with chronic periodontitis (CP). A total of one hundred and one individuals, 59 controls and 42 patients with CP, participated in this study. Clinical index measurements were recorded during the periodontal examination, and radiographic eva